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自体血清皮肤试验在慢性特发性荨麻疹自身免疫机制异常诊断中的应用价值

郝国娈 沃晓枫 顾科峰 沈东 高宜云

浙江医学2011,Vol.33Issue(8):1168-1170,3.
浙江医学2011,Vol.33Issue(8):1168-1170,3.

自体血清皮肤试验在慢性特发性荨麻疹自身免疫机制异常诊断中的应用价值

Autologous serum skin test in diagnosis of chronic idiopathic urticaria with autoimmunity

郝国娈 1沃晓枫 1顾科峰 1沈东 1高宜云1

作者信息

  • 1. 311203,杭州市萧山区皮肤病医院
  • 折叠

摘要

Abstract

Objective To assess the autologous serum skin test (ASST) in diagnosis of chronic idiopathic urticaria (CIU) with autoimmunity.Methods ASST was performed in 90 patients with CIU.The clinical features of the patients with ASST+ were evaluated and compared with those of the patients with ASST-.Results ASST was positive in 20 out of 90 CIU cases with a positive rate of 22.2%.There was no significant difference in age and sex distribution of the disease between the ASST+ and ASST- CIU patients (P>0.05); and there was also no significant difference in the total score of physical signs and symptoms and eruption frequency between the ASST+ and ASST- patients (P>0.05).But ASST+ patients had a significant longer course (P<0.05) than ASST- patients.ASST+ patients had more frequent autoimmune conditions than ASST- patients (P<0.05).More organ- specific autoantibodies were found in ASST+ patients than in ASST- patients.Conclusion ASST can be used as a screening test for autoantibodies in CIU.

关键词

自体血清皮肤试验/慢性特发性荨麻疹/自身免疫疾病

Key words

Autologous serum skin test / Chronic idiopathic urticaria / Autoimmune diseases

引用本文复制引用

郝国娈,沃晓枫,顾科峰,沈东,高宜云..自体血清皮肤试验在慢性特发性荨麻疹自身免疫机制异常诊断中的应用价值[J].浙江医学,2011,33(8):1168-1170,3.

浙江医学

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