浙江医学2011，Vol.33Issue(8)：1165-1167,3.
98例迟发性呼吸机相关性肺炎患者的病原学及耐药性监测
Pathogenesis and drug resistance in 98 Patients with late-onset ventilator-associated pneumonia
屠越兴 1俞云松 1李茜 2韩芳 2江玲芝2
作者信息
- 1. 310016,杭州,浙江大学医学院附属邵逸夫医院感染科
- 2. 浙江省人民医院感染科
- 折叠
摘要
Abstract
Objective To probe the pathogenesis and their resistance to antibiotics of late- onset ventilator- associated pneumonia (VAP). M ethods A clinical trial in late- onset VAP episodes of 98 patients receiving mechanical ventilation, The pathogenesis and their resistance to antibiotics were analyed. Results A total of 168 pathogen strains were isolated through fiberbronchoscopy by bacterial culture,The Gram- negative bacteria (GNB)were 82.9％, Non- fermenters were 51.4％ and Enterobacteriaceae were 32.7％ among it ,The Gram- positive bacteria were 13.5％,the fungi 4.6％.The top three pathogen strains with VAP were Acinetobacter baumanii(26.9％),Pseudomonas aeruginosa(13.6％),Kleb siella pneumoniae(10.5％) .GNB were highly resistant to common antimicrobials and demonstrated multi-drug resistance, Drug resistance of the Gram-positive bacteria to vancomycin was Conclusion The major pathogenic bacteria in late- onset VAP is GNB, and there are often demonstrated multi- drug resistance,It is suggested that empiric antimicrobial therapy for patients with late- onset VAP should base on the surveillance of etiology and resistance .关键词
呼吸机相关性肺炎/抗生素/耐药性/纤维支气管镜/病原学Key words
Ventilator- associated pneumonia/ Antibiotics / Drug resistance/ Branchofiberoscope/ Etiology引用本文复制引用
屠越兴,俞云松,李茜,韩芳,江玲芝..98例迟发性呼吸机相关性肺炎患者的病原学及耐药性监测[J].浙江医学,2011,33(8):1165-1167,3.
