Cytogenetic characteristics of B cell chronic lymphocytic leukemia in 275 Chinese patients by fluorescence in situ hybridization: a multicenter studyOACSCDCSTPCD
Cytogenetic characteristics of B cell chronic lymphocytic leukemia in 275 Chinese patients by fluorescence in situ hybridization: a multicenter study
Background Under conventional cytogenetic (CC) analysis, only 30%-50% of B cell chronic lymphocytic leukemia (B-CLL) cases show clonal aberrations. Using fluorescence in situ hybridization (FISH), the percentage of patients with abnormalities rises to almost 80%, among them, the most frequent abnormalities were 13q14, 11q22, p53 deletions and trisomy 12. The aim of this study was to explore the incidence of cytogenetic changes in Chinese patients with B-CLL.…查看全部>>
LAI Yue-yun;HUANG Xiao-jun
Peking University Institute of Hematology, Peking University People's Hospital, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing 100044, ChinaPeking University Institute of Hematology, Peking University People's Hospital, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing 100044, China
cytogeneticschronic lymphocytic leukemiain situ hybridization, fluorescence
cytogeneticschronic lymphocytic leukemiain situ hybridization, fluorescence
《中华医学杂志（英文版）》 2011 (16)
2417-2422,6
This study was supported by a grant from the China Ministry of Health (No.WKJ2007-3-001).
评论