现代检验医学杂志2011，Vol.26Issue(4)：114-115,2.DOI:10.3969/j.issn.1671-7414.2011.04.039
同一医院内两台凝血分析仪血浆凝血酶原时间的可比性验证
王薇 1陆学军 2李少男 1钟堃 1白玉 1王治国1
作者信息
- 1. 卫生部北京医院,卫生部临床检验中心,北京,100730
- 2. 卫生部北京医院,检验科,北京,100730
- 折叠
摘要
Abstract
Objective To verify the comparability of patients results of PT by two different types of instrument in one hospital. Methods The procedures of range comparison method include :selecting comparison analysis materials.selecting instruments,calculating analysis material concentrations which were approaching the tests of comparability,calculating the concentrations or activities of expectations which could used to select comparable samples,selecting comparable samples,setting critical differentials of comparability tests,acceptable standards of patients results comparability tests,ensuring the number of test replication. Results Laboratories should evaluate the comparability of PT between major analysis instruments and reserved instruments. The imprecision levels of two types of analysis instruments were both 3 ％. Sample ranges were 13±13 × 20％ (10. 4s～15. 6s) and 25±25 × 20％ (20. 0s ～30. 0s ). Selected 14. 2s (sample 1) and 27. 1s (sample 2)as the initial values of major analysis instruments. The acceptable standard of critical differentials was intended to be 15％.According to the critical differentials (％) of studentized range tests and the information forward we could choose patient samples of two different levels while each sample only test once for each analysis instruments for testing whether there was difference between them. The mean percentage ranges for two analyzers results of each kind of samples were 6. 14％and 17. 51％ respectively while the adjusted percentage ranges were 3. 86 ％ and 2. 51％. Because the absolute values of the adjusted ranges were smaller than critical differentials,the comparability of the two methods for the given standard was acceptable. Conclusion Range test method supplies a guideline for evaluating the comparability for different systems in one health care system of the same patient sample.关键词
准确度/偏倚/变异系数/互通性/可比性/不精密度Key words
accuracy/bias /coefficient of variation/commutable / comparability/imprecision分类
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王薇,陆学军,李少男,钟堃,白玉,王治国..同一医院内两台凝血分析仪血浆凝血酶原时间的可比性验证[J].现代检验医学杂志,2011,26(4):114-115,2.
