重庆医学2011，Vol.40Issue(27)：2709-2710,2713,封2,4.DOI:10.3969/j.issn.1671-8348.2011.27.003
牛颈静脉带瓣管道重建犬右心室流出道及其血流动力学研究
Hemodynamic study of right ventricular outflow tract reconstruction with valved boving jugular vein conduit in canine model
摘要
Abstract
Objective To investigate the hemodynamic performance of valved bovine jugular vein conduits(VBJVC) for right ventricular outflow tract reconstruction in canine model.Methods The VBJVC that were treated with the glutaraldehyde(GA) were implanted between the pulmonary artery and right ventricle in six canines.Use cardiac catheterization to measure right ventricular and pulmonary artery pressures before and after one to two years the implantation.Hemodynamic evaluation were carried out by united echocardiography and right ventricular angiography.Results The canine 1 was died at 24 hours after operation,canine 2,4 ,5 surrived 14 to 18 mothes, the canine 3,6 survived more than two years.The right ventricular and pulmonary artery pressure (including systolic pressure, diastolic pressure and mean pressure) had not significantly changed before and after one to two years the right ventricular outflow tract reconstrution.The systolic pressure gradients between the right ventricle and the pulmonary artery from 1.0 to 2.4 mm Hg.The right ventricular diastolic pressure had not increased.After one to two years reconstruction with the VBJVC the echocardiography and right ventricular angiography showed the conduit had no obvious obstruction and valve motion no obvious regurgitation with no obvious thickening of the leaflets.Conclusion The GA fixed VBJVC has good hemodynamic performance of right ventricular outflow tract reconstruction in canine.关键词
颈静脉/血流动力学/右心室流出道Key words
jugular veins / hemodvnamics / right ventricular outflow tract引用本文复制引用
何德沛,严宇,吴洪坤,余扬,罗永金,李正恭,谢英,杜耘..牛颈静脉带瓣管道重建犬右心室流出道及其血流动力学研究[J].重庆医学,2011,40(27):2709-2710,2713,封2,4.基金项目
重庆市科委科技攻关基金资助项目(CSTC2007AC5020). （CSTC2007AC5020）
