重庆医学2011，Vol.40Issue(25)：2527-2528,2531,3.DOI:10.3969/j.issn.1671-8348.2011.25.013
3种药联合盐酸替罗非班治疗急性冠状动脉综合征患者的疗效观察
Efficacy of three-drug combination tirofiban hydrochloride on patients with acute coronary syndrome
汪亚芸 1陈曼华1
作者信息
- 1. 湖北省武汉市中心医院心内科,430014
- 折叠
摘要
Abstract
Objective To study the clinic curative and safety of tirofiban hydrochloride combined with applying aspirin,clopidogrel, low molecular weight heparin(LMWH) on patients with acute coronary syndrome [unstable angina(UA)or non-ST-segment elevation myocardial infarction(NSTEMI)]. Methods 120 cases of hospitalized patients with acute coronary syndrome were selected and divided into observation group (61 cases) and control group(59 cases). The two groups took aspininand chopidogrd of the same dosage besides taking tirofiban hydrochloride,the observation group was injectied with hypodermicly LMWH. But in control group,only LMWH was given. Results All caused death in 8 days, refractory angina pectoris of observation group and control group were decreased apparently(P＜0.05). After administration the inhibition of platelets aggregations was evidently decreased in observation group than control group(P＜0.01). In mild hemorrhage,there was significant difference in two groups(P＜0.05). In observation group 61 patients' platelet count decreased after being given tirofiban hydrochloride(P＜0.05), but it's still in normal range. APTT value increased slightly in observation group(P＜0.05), but not exceeded its two times value of normal. Conclusion Combining tirofiban hydrochloride on the base of applying aspirin, clopidogrel,low molecular weight heparin(LMWH) to treat patients with acute coronary syndrome is effective and safe.关键词
替罗非班/不稳定性心绞痛/急性非ST段抬高性心肌梗死Key words
tirofiban hydrochloride/ unstable angina(UA) /Non-ST-segment elevation myocardial infarction(NSTEMI)引用本文复制引用
汪亚芸,陈曼华..3种药联合盐酸替罗非班治疗急性冠状动脉综合征患者的疗效观察[J].重庆医学,2011,40(25):2527-2528,2531,3.
