重庆医学2011，Vol.40Issue(27)：2722-2723,2.DOI:10.3969/j.issn.1671-8348.2011.27.008
血清胃蛋白酶原在胃癌及胃癌前病变诊断中的意义
The value of serum PG in diagnosis of gastric cancer and gastric precancerous lesions
摘要
Abstract
Objective To evaluate the clinical value of the serum levels of pepsinogen Ⅰ (PG Ⅰ ), pepsinogen Ⅱ (PG Ⅱ ) and PG Ⅰ/PG Ⅱ in diagnosis of gastric cancer and gastric precancerous lesions. Methods 539 cases were included in the study. According to the results of gastroscopy and histopathology, these patients were divided into five groups, gastric ulcer group with 124 cases, superficial gastritis group with 130 cases,atrophic gastritis group with 102 cases,gastric cancer with 90 cases,and normal group with 93 cases,and then the serum levels of PG Ⅰ ,PG Ⅱ of each group are compared. Results The PG Ⅰ level of gastric ulcer patients was significantly higher than that of healthy group and the orher groups(P＜0.01). The PGR in CAG and GC patients was significantly lower than that in the other groups(P＜0.01). Conclusion The plasma levels of the serum levels of PG Ⅰ ,PG Ⅱ and PG Ⅰ / PGⅡ play an important value in diagnosis of gastric cancer and gastric precancerous lesions.关键词
胃蛋白酶原类/胃肿瘤/胃癌前病变Key words
pepsinogens / stomach neoplasms / precancerous lesions引用本文复制引用
易楠,王珏,王江红..血清胃蛋白酶原在胃癌及胃癌前病变诊断中的意义[J].重庆医学,2011,40(27):2722-2723,2.基金项目
重庆市卫生局基金资助项目(2009-2-132). （2009-2-132）
