重庆医学2011，Vol.40Issue(25)：2516-2517,2519,3.DOI:10.3969/j.issn.1671-8348.2011.25.008
色氨酸免疫吸附在神经系统自身免疫性疾病中的应用
The effect of tryptophan immunoadsorption therapy on neurological autoimmune diseases
肖龙 1古英明 1蔡扬 1黄莹 1张莹1
作者信息
- 1. 广州医学院附属第二医院血液净化科,广州,510260
- 折叠
摘要
Abstract
Objective To observe effects and complications of tryptophan immunoadsorption(IA) therapy on neurological auto immune diseases. Methods From April 2007 to February 2010,14 patients(10 male,4 female) with neurological autoimmune disea ses were given immunoadsorbent therapy using the tryptophan column (IMMUSORBA TR-350, ASAHI KASEI MEDICAL CO,LTD) in addition to drug therapy. Results Clinical symptom of all patients improved after IA therapy. Muscular performance was increased 1 to 2 grades. 5 patients regained full muscle power. Serum immunoglobulins of IgG,IgA and IgM decreased significantly after adsorption(P＜0.05). Of the 54 procedures in IA patients, 4 procedures occurred adverse effects,induching 3 times of hypotension and 1 time of mouth anesthesia. All adverse effects were well controlled by symptomatic therapy. Conclusion Tryptophan IA was a safe and effective therapy on neurological autoimmune diseases. Serum immunoglobulins decrease significantly after adsorption.关键词
色氨酸/免疫吸附/神经系统自身免疫性疾病Key words
tryptophan / immunoadsorption / neurological autoimmune diseases引用本文复制引用
肖龙,古英明,蔡扬,黄莹,张莹..色氨酸免疫吸附在神经系统自身免疫性疾病中的应用[J].重庆医学,2011,40(25):2516-2517,2519,3.
