医疗卫生装备2011，Vol.32Issue(8)：94-95,104,3.
回旋加速器日连续2次生产《'18》F-离子时产量差异分析
Difference Analysis of Continual 《'18》F-ion Production Twice a Day by Cyclotron
郭李磊 1赵晋华 1乔文礼 1姚玉平 1杨毅2
作者信息
- 1. 200080,上海,上海交通大学附属第一人民医院核医学科
- 2. 200080,上海,通用电气公司
- 折叠
摘要
Abstract
Objective G.E. Minitrace Cyclotron was used to produce 18F- ion twice a day with nuclear reaction 18O(p, n)18F. The I8F- ion activities of the second time were statistically higher than the first time when the conditions of production were different. This study assessed whether the 18F- ion activities of the second time were higher than the first time when the conditions of production were control. Methods I8F- ion was produced twice a day when the conditions of production, including the irradiation current, the irradiation time and the batch of 18O-H2O, were control. The results were analyzed to show whether the 18F- ion activities of the second time in ten days were statistically higher than the first time using paired samples T-test by SPSS 17.0. Results The mean 18F- ion activity of the second time was 831.45 ±54.05mCi, which was higher than that of the first time (746.24±11.75mCi) (P＜0.005). Conclusion When the conditions of production are control, the I8F- ion activities of the second time are higher than the first time. The influence factors include the I8O-H2O concentration in the cavity of target, the remnant I8F- ion in the tube and filter transferring to the target bottle at the secondproduction and air humidity.[Chinese Medical Equipment Journal,2011,32(8):94-95,104]关键词
回旋加速器/《'18》F-离子活度/平均秉流/轰靶时间/《'18》O-H《,2》O浓度Key words
cyclotron/ 18F- ion activity/ average current/ irradiation time/ 18O-H2O concentration分类
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郭李磊,赵晋华,乔文礼,姚玉平,杨毅..回旋加速器日连续2次生产《'18》F-离子时产量差异分析[J].医疗卫生装备,2011,32(8):94-95,104,3.
