中国全科医学2011，Vol.14Issue(26)：3025-3027,3.
儿童微小病变性肾病综合征临床分析
Renal Pathology of Minimal Change Nephrotic Syndrome in Children:Report of 222 Cases
任献国 1刘光陵 1夏正坤 1高远赋 1樊忠民 1何旭 1茅松1
作者信息
- 1. 210003,江苏省南京市,南京军区南京总医院儿科
- 折叠
摘要
Abstract
Objective To analyze the relationship between glucocorticosteroid - responsiveness, age, clinical manifestations and immunofluorescence type in children with minimal change nephrotic syndrome. Methods The patients were divided as the infant group, the toddler group, the preschool group, the school group and the adolescence group according to age. According to clinical manifestations, those children were divided as the simple group and the nephritic group. According to clinical outcomes of four weeks of glucocorticosteroid therapy, those children were divided as the complete remission group, the partial remission group and the non - remission group. Results After 4 weeks of glucocorticosteroid therapy , the highest complete remission rate was noted in the preschool group, followed by the school group. The rates of complete remission, partial remission and non - remission were 80.4％ , 16.0％ , 3.6％ and 39.3％, 42.9％, 17.8％ in the simple and the nephritic group, respectively. Patients with the pathology type of IgA + M + G + C3 showed the worst hormone response. Patients of IgM deposition pathology had worse response than IgA. Patients of complement deposition or non - immunocomplex deposition pathology showed satisfiable hormone responses. Conclusion The outcomes of four - week glucocorticosteroid therapy are correlated with age , clinical manifestations and immunofluorescence types in patients with minimal change nephrotic syndrome.关键词
肾病综合征/肾病/脂性/激素类/儿童Key words
Nephrotic syndrome/ Nephrosis, lipoid/ Hormones/ Child分类
医药卫生引用本文复制引用
任献国,刘光陵,夏正坤,高远赋,樊忠民,何旭,茅松..儿童微小病变性肾病综合征临床分析[J].中国全科医学,2011,14(26):3025-3027,3.
