医学分子生物学杂志2011，Vol.8Issue(4)：368-371,4.DOI:10.3870/j.issn.1672-8009.2011.04.018
FOXl2基因的研究现状
Study of FOXL2 Gene
雷涛 1廖世波 1段迎春2
作者信息
- 1. 湖北医药学院第三临床学院,湖北省十堰市,442000
- 2. 湖北医药学院附属十堰市人民医院妇产科,湖北省十堰市,442000
- 折叠
摘要
Abstract
FOXL2 is a single-exon gene encoding a forkhead transcription factor, which is located at 3q23. Nomal expression of FOXL2 is important to maintain female gender characteristics. Mutations in FOXL2, however, are likely to result in abnomity of female characteristics. FOX12 mutation causes BPES. Its mutations can be detected in POF patients. FOX13 is considered as an early regulator of ovarian development. In addition, it has been suggested that mutations in FOXL2 are relative to reproductive system tumors.关键词
FOXL2基因/先天性睑裂狭小综合征/基因突变/卵巢早衰Key words
FOXL2 gene/ BPES/ gene mutation/ POF分类
医药卫生引用本文复制引用
雷涛,廖世波,段迎春..FOXl2基因的研究现状[J].医学分子生物学杂志,2011,8(4):368-371,4.
