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酸枣仁总黄酮抗抑郁作用的实验研究

赵启铎 舒乐新 王颖 牟佳佳 宋志国 李金梅

天津中医药2011,Vol.28Issue(4):335-337,3.
天津中医药2011,Vol.28Issue(4):335-337,3.

酸枣仁总黄酮抗抑郁作用的实验研究

Study on the antidepressant effect of total flavonoids from Semen Ziziphi Spinosae

赵启铎 1舒乐新 1王颖 1牟佳佳 1宋志国 2李金梅2

作者信息

  • 1. 天津中医药大学中药学院,天津,300193
  • 2. 吉林熬东集团大连药业股份有限公司,大连,116043
  • 折叠

摘要

Abstract

[Objective] To observe the antidepressant effect of total flavonoids from Semen Ziziphi Spinosae in mice. [Methods] To inves tigate the antidepressant activity of total Flavonoids from Semen Ziziphi Spinosae by the forced swimming test and the tail suspension test, with behavioral despair mice in the immobility time as an indicator. [Results] Different dose groups of total flavonoids from Semen Ziziphi Spinosae could significantly reduce the immobility time of mice during the forced swimming test and the tail Suspension test, compared with that of the control group (P<O.05); compared with that of the positive group (P<O.05). [Conclusion] The total flavonoids from Semen Ziziphi Spinosae possess had significant antidepressant effects.

关键词

酸枣仁/总黄酮/抗抑郁/行为绝望

Key words

Semen Ziziphi Spinosae/ total flavonoids/ antidepressant effect/ behavioral despair

分类

医药卫生

引用本文复制引用

赵启铎,舒乐新,王颖,牟佳佳,宋志国,李金梅..酸枣仁总黄酮抗抑郁作用的实验研究[J].天津中医药,2011,28(4):335-337,3.

基金项目

天津市高等学校发展项目基金(20070305). (20070305)

天津中医药

OACSTPCD

1672-1519

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