天津中医药2011,Vol.28Issue(4):335-337,3.
酸枣仁总黄酮抗抑郁作用的实验研究
Study on the antidepressant effect of total flavonoids from Semen Ziziphi Spinosae
摘要
Abstract
[Objective] To observe the antidepressant effect of total flavonoids from Semen Ziziphi Spinosae in mice. [Methods] To inves tigate the antidepressant activity of total Flavonoids from Semen Ziziphi Spinosae by the forced swimming test and the tail suspension test, with behavioral despair mice in the immobility time as an indicator. [Results] Different dose groups of total flavonoids from Semen Ziziphi Spinosae could significantly reduce the immobility time of mice during the forced swimming test and the tail Suspension test, compared with that of the control group (P<O.05); compared with that of the positive group (P<O.05). [Conclusion] The total flavonoids from Semen Ziziphi Spinosae possess had significant antidepressant effects.关键词
酸枣仁/总黄酮/抗抑郁/行为绝望Key words
Semen Ziziphi Spinosae/ total flavonoids/ antidepressant effect/ behavioral despair分类
医药卫生引用本文复制引用
赵启铎,舒乐新,王颖,牟佳佳,宋志国,李金梅..酸枣仁总黄酮抗抑郁作用的实验研究[J].天津中医药,2011,28(4):335-337,3.基金项目
天津市高等学校发展项目基金(20070305). (20070305)