中国组织工程研究与临床康复2011,Vol.15Issue(27):5108-5111,4.DOI:10.3969/j.issn.1673-8225.2011.27.038
骨髓间充质干细胞的分离培养与鉴定
Isolation, cultivation and identification of bone marrow mesenchymal stem cells
摘要
Abstract
BACKGROUND: Bone marrow mesenchymal stem cells (BMMSCs) are currently a hot subject of research in many fields such as tissue engineering, cells transplantation and gene therapy. OBJECTIVE: To review the biological property, isolation, cultivation and clinical application of BMMSCs.METHODS: We had retrieved 30 relevant articles from CNKI and PubMed databases with the key words of “bone marrow mesenchymal stem cells, isolation, cultivation, identification” in Chinese and English, respectively, between January 1995 to January 2010 respectively.RESULTS AND CONCLUSION: BMMSCs are nonhematopoietic stem cells and easy to be harvested and cultured which show varying differentiation and high proliferation potentials. BMMSCs can differentiate into osteoblasts, chondrocytes, lipocytes,myocardial cells, nerve cells and hepatocytes, and have become an important seed cells for tissue engineering.关键词
骨髓间充质干细胞/分离/培养/鉴定/综述文献分类
基础医学引用本文复制引用
胡彬,刘晓华,赵林..骨髓间充质干细胞的分离培养与鉴定[J].中国组织工程研究与临床康复,2011,15(27):5108-5111,4.基金项目
2009 年青岛市公共领域科技支撑计划项目(09-1-1-25-nsh). (09-1-1-25-nsh)