中国组织工程研究与临床康复2011，Vol.15Issue(31)：5781-5784,4.DOI:10.3969/j.issn.1673-8225.2011.31.019
亲属活体供肾移植中供者肾功能的评估
Evaluation of donor's renal function during living-related donor kidney transplantation
赵豫波 1石炳毅 2方佳丽 3陈正 3潘光辉 3陈建兵 3王科 4高振利4
作者信息
- 1. 解放军海军总医院泌尿外科,北京市,100048
- 2. 解放军总医院第二附属医院全军器官移植中心,北京市,100091
- 3. 广州医学院第二附属医院器官移植中心,广东省广州市,510260
- 4. 青岛大学医学院附属烟台毓璜顶医院泌尿外科,山东省烟台市264000
- 折叠
摘要
Abstract
BACKGROUND: Proper effective evaluation of bilateral renal function before kidney transplantation is of importance for the safety of donors and recipients during living-related donor kidney transplantation. OBJECTIVE: To investigate the suitable indexes for evaluating living donor's renal function in living-related donor kidney transplantation.METHODS: A total of 173 cases of living-related donor kidney transplantation were analyzed retrospectively. The donor grafts were divided into two groups: elderly group (≥ 55 years) and young- and middle-aged group (＜ 55 years). Before kidney transplantation, there was no significant difference in the indexes which reflect renal function, including serum creatinine, total glomerular filtration rate (GFR), remaining renal GFR, endogenous creatinine clearance rate, and blood urea nitrogen. Change in each index of renal function was compared before and after kidney transplantation.RESULTS AND CONCLUSION: Compared with before transplantation, serum cre atinine and blood urea nitrogen levels were increased while renal total GFR was decreased at 10 days after transplantation (P ＜ 0.01). At 1 month after transplantaton, remaining renal total GFR was increased (P = 0.0000), but it increased compared with before transplantation. These findings suggest the renal total GFR can be used as a main index for evaluating the donor's renal function during living-related donor kidney transplantation, but it would provide more reliable information if combining with serum creatinine and endogenous creatinine clearance rate.关键词
亲属活体供者/肾移植/肾小球滤过率/肌酐/尿素氮/99锝m-二乙三胺五乙酸分类
临床医学引用本文复制引用
赵豫波,石炳毅,方佳丽,陈正,潘光辉,陈建兵,王科,高振利..亲属活体供肾移植中供者肾功能的评估[J].中国组织工程研究与临床康复,2011,15(31):5781-5784,4.
