中国组织工程研究与临床康复2011，Vol.15Issue(34)：6351-6354,4.DOI:10.3969/j.issn.1673-8225.2011.34.020
短碳纤维增强聚醚醚酮为全髋假体材料的生物相容性及力学性能
Short carbon fiber reinforced polyetgeretherketone for hip prosthesis: Biocompatibility and biomechanics
摘要
Abstract
BACKGROUND: Polyetgeretherketone has good biocompatibility, but its modulus and mechanical strength characteristics dropbadly upon glass-transition temperature, so as to fail to provide a steady condition for bone growth.OBJECTIVE: To observe the biocompatibility and biomechanics of short carbon fiber reinforced polyetgeretherketone as hipprosthesis by animal experiment.METHODS: The biocompatibility in vitro was measured by MTT, hemolysis test, acute toxicity experiment and pyrogenexperiment; SCF/PEEK composite plates were implanted into the rabbits, and the formation of fibrous capsules and generaltissues conditions around the plates were observed under the optical microscope; The stress tests were carried on the WE-SAuniversal testing machine.RESULTS AND CONCLUSION: The relative survival rate was ＞ 75％, the hemolysis rate ＜ 5％, indicating a good bloodcompatibility. There was no evident difference between the two groups. As the time goes on, the relation between theimplanted-plates and capsules was more and more close, and inflammatory cells became gradually less.关键词
短碳纤维/聚醚醚酮/髋关节/应力测试/生物相容性/生物材料分类
基础医学引用本文复制引用
王克军,郭卫春,唐谨,余铃,赵胜豪..短碳纤维增强聚醚醚酮为全髋假体材料的生物相容性及力学性能[J].中国组织工程研究与临床康复,2011,15(34):6351-6354,4.基金项目
武汉大学研究生基金资助项目. （）
