临床神经病学杂志2011，Vol.24Issue(4)：254-257,4.
320排容积CT指导下脑梗死超早期静脉溶栓的疗效观察
Observe the effect of vein thrombolytic therapy by the guide of 320 slices volume CT in the earliest period of cerebral infarction
张青山 1孙卫红 2黄颖 1李光超 2王涛 2魏涛 1曹伟 2赵宝忠2
作者信息
- 1. 221009,徐州市中心医院神经三科
- 2. 221009,徐州市中心医院CT室
- 折叠
摘要
Abstract
Objective To observe the effect of vein thrombolytic therapy by the guide of 320 slices volume CT in the earliest period cerebral infarction. Methods Eleven patients with acute cerebral infarction ( ACI ) whose course ＜4.5 h were examined by the 320 slices volume CT. The vein thrombolytic therapy with ft-PA at the earliest period was applied by the guide of this test result. The scores of National Institutes of Health Stroke Scale (NIHSS) and modified Edinbergh-Scandinavia stroke scale(MESSS) were took before and after the treatment 24 h and 14 d,and the therapeutic effect were evaluated. Results There was no obvious responsibility focus of infarction in the 11 ACl patients by skull CT plain scan images. The CT angiography showed that the cerebral vessels in the reqine corresponding to the lesion were obvious rare. Seven cases had angiostenosis which corresponding to the infarction lesion. Four cases had vascular occlusion, including 2 cases had compensatory blood vessel formation. The CI perfusion showed the regional cerebral blood flow (rCBF) in the regine corresponding the clinical symptoms in 9 cases were descrsed. Regional cerebral blood volume (rCBV) in the regine corresponding the clinical symptoms were slight increased in 7 cases, decreased in 2 cases, and 2 cases had no change. MTT and TIP were obvious extension at 14 d after thrombolysis treatment. The NIHSS and MESSS scores after thrombolysis treatment 24 h and 14 d were significantly lower than before treatment ( all P ＜ 0. O1 ). Six cases were basio-healing. Two cases were significant progressive. Two cases were progressive, and 1 case was no change. Conclusions 320 slices volume CT can reflect the perfusion condition of cerebral vessel and its tissue unit in the earliest period of cerebral infarction. And which can guide the thrombolytic therapy to save the damage brain tissue caused by ischemia.关键词
320排CT/脑梗死/重组组织型纤溶酶原激活剂/溶栓Key words
320 slices volume CT/ cerebral infarction/ rt-PA/ thrombolysis分类
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张青山,孙卫红,黄颖,李光超,王涛,魏涛,曹伟,赵宝忠..320排容积CT指导下脑梗死超早期静脉溶栓的疗效观察[J].临床神经病学杂志,2011,24(4):254-257,4.
