摘要
Abstract
Objective To study the effects of acute normovolemic hemodilution(ANH)combined with controlled hypotension (CH) on hemodynamics and oxygen metabolism during brain tumors operation. Methods Sixty patients adoped from 2008 to 2009 in our hospital were randomly divided into two groups:ANH combined CH group(group A,n= 30)and pure CH group (group B,n=30). The mean arterial pressure(MAP) , heart rate, central renous pressure(CVP), cardiac output, systemic vascular resistance (SVR) ,lactate(LAC), hematocrit(Hct) were recorded on the set time point, and the oxygen delivery, consumption of orygen, and oxygen extraction ration(ERO2) were calculated. Results There were significant differences of MAP, heart rate,CVP, cardiac out put,SVR, LAC, hematocrit(Hct) , oxygen delivery, consumption of orygen, and oxygen extraction ration(ERO2 ) at different time points between the two groups(P＜0.05). Conclusion Preoperative ANH combined CH is helpful for the stable of hemodynamics in patients during brain tumors operation lohich,does not affect the body's oxygen metabolism, and can reduce intraoperative blood transfusion effectively.关键词
血液稀释/低血压/控制性降压/血流动力学/氧代谢Key words
hemodilution/ hypotension/ controlled hypotension/ hemodynamics/ oxygen metabolism
