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小儿复方氨基酸注射液与5%碳酸氢钠注射液配伍稳定性考察

蔡伟明 陈红明

中国药业2011,Vol.20Issue(17):13-14,2.
中国药业2011,Vol.20Issue(17):13-14,2.

小儿复方氨基酸注射液与5%碳酸氢钠注射液配伍稳定性考察

Pediatric Compound Amino Acid Injection with 5%Sodium Bicarbonate Injection Compatibility Observation

蔡伟明 1陈红明1

作者信息

  • 1. 广东医学院附属医院药学部,广东,湛江,524001
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摘要

Abstract

Objective To observe the compatible stability of pediatric Compound Amino Acid Injection(18AA- Ⅰ) mixed with 5% Sodium Bicarbonate Injection,and to provide a reference for clinical compatibility.Methods simulating the clinical use,the appearance, pH and particulate matter changes of the mixed solutions were observed in 0-5 h.Results No significant change in appearance, but pH was changed in the range of 6.73-7.06; the number of particulate matter increased significantly in 3-5 h.Conclusion Pediatric Compound Amino Acid Injection( 18AA- Ⅰ ) should be used separately in order to avoid the increase number of particulate matter which caused the rise of incidence rate of adverse reactions.

关键词

小儿复方氧基酸注射液/碳酸氢钠注射液/配伍/不溶性微粒

Key words

Pediatric Compound Amino Acid Injection /Sodium Bicarbonate Injection /compatibility/particulate matter

分类

医药卫生

引用本文复制引用

蔡伟明,陈红明..小儿复方氨基酸注射液与5%碳酸氢钠注射液配伍稳定性考察[J].中国药业,2011,20(17):13-14,2.

中国药业

OACSTPCD

1006-4931

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