中国药业2011,Vol.20Issue(17):26-27,2.
差示分光光度法测定盐酸异丙嗪糖浆中盐酸异丙嗪含量
Determination of Promethazine Hydrochloride in Promethazine Hydrochloride Syrup by Differential Spectrophotometry
王芳 1宋光伟 1刘晓方 1曹健1
作者信息
- 1. 第三军医大学新桥医院药学部,重庆,400037
- 折叠
摘要
Abstract
Objective To establish a differential spectrophotometry method for determining the content of the promethazine hydrochloride in its syrup. Methods The content of promethazine hydrochloride was examined by utilizing differential spectrophotometry at the detection wavelength of 336. 5 nm. Results There was a good linear relationship in the concentration range of 10. 00 -50. 02 μg/mL( r =0. 999 9); the average recovery rate was 99. 82% , RSD =0. 23% ( n =6) . Conclusion It is a simple, accurate, reliable, reproducible and specific method for determining the promethazine hydrochloride in its syrup.关键词
盐酸异丙嗪糖浆/盐酸异丙嗪/差示分光光度法/含量测定Key words
Promethazine Hydrochloride Syrup/ promethazine hydrochloride/ differential spectrophotometry/ content determination分类
医药卫生引用本文复制引用
王芳,宋光伟,刘晓方,曹健..差示分光光度法测定盐酸异丙嗪糖浆中盐酸异丙嗪含量[J].中国药业,2011,20(17):26-27,2.