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Environmental enrichment promotes neural remodeling in newborn rats with hypoxic-ischemic brain damage

Chuanjun Liu Yankui Guo Yalu Li Zhenying Yang

中国神经再生研究(英文版)2011,Vol.6Issue(20):1548-1553,6.
中国神经再生研究(英文版)2011,Vol.6Issue(20):1548-1553,6.DOI:10.3969/j.issn.1673-5374.2011.20.005

Environmental enrichment promotes neural remodeling in newborn rats with hypoxic-ischemic brain damage

Environmental enrichment promotes neural remodeling in newborn rats with hypoxic-ischemic brain damage

Chuanjun Liu 1Yankui Guo 2Yalu Li 3Zhenying Yang1

作者信息

  • 1. Department of Pediatrics, Taian Health Centre for Women and Children, Taian 271000, Shandong Province, China
  • 2. Central Laboratory of Shandong Agricultural University, Taian 271018, Shandong Province, China
  • 3. Morphological Laboratory of Taishan Medical College, Taian 271000, Shandong Province, China
  • 折叠

摘要

Abstract

We evaluated the effect of hypoxic-ischemic brain damage and treatment with early environmental enrichment intervention on development of newborn rats, as evaluated by light and electron microscopy and morphometry. Early intervention with environmental enrichment intelligence training attenuated brain edema and neuronal injury, promoted neuronal repair, and increased neuronal plasticity in the frontal lobe cortex of the newborn rats with hypoxic-ischemic brain damage.

关键词

intelligence training/environmental enrichment/synaptic plasticity/newborn rats/hypoxic-ischemic brain damage/neural regeneration

Key words

intelligence training/environmental enrichment/synaptic plasticity/newborn rats/hypoxic-ischemic brain damage/neural regeneration

引用本文复制引用

Chuanjun Liu,Yankui Guo,Yalu Li,Zhenying Yang..Environmental enrichment promotes neural remodeling in newborn rats with hypoxic-ischemic brain damage[J].中国神经再生研究(英文版),2011,6(20):1548-1553,6.

中国神经再生研究(英文版)

OACSCDSCI

1673-5374

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