中国全科医学2011，Vol.14Issue(26)：2949-2952,4.
社区糖尿病视网膜病变及危险因素探讨
Prevalence and Risk Factors of Diabetic Retinopathy in Cuigezhuang Community of Beijing
摘要
Abstract
Objective To understand the prevalence and risk factors of diabetic retinopathy ( DR ) in patients with diabetes mellitus ( T2DM ) in Cuigezhuang community and to provide reference for diabetic blindness prevention. Methods Cluster sampling method was applied and Cuigezhuang community was enrolled in the study of jointed management of type 2 diabetes by grade A class 3 hospitals and multiple community health centers ( Aug. 2008 ) . A total of 329 T2DM patients entered the study voluntarily and finished investigation forms under the guidance of specially trained physicians. Physical and laboratory examinations were also carried out on these subjects. Results Seventy - four out of the 329 cases were with diabetic retinopathy [ prevalence rate, 22.49％, 95％ CI ( 17.98％, 27.00％ )]; non - proliferative and proliferative retinopathy accounted for 89.2％ and 10.8％ respectively. DR incidence rate decreased as the income grew ( P = 0.031 ), while increased with the increase of duration ( P ＜ 0.01 ) and HhA1c level ( P＜0.01 ). With the influence among individual factors adjusted, compared with patients with incomes less than 1000 Yuan/month, those with incomes between 1000 and 2000 Yuan/month and more than 2000 Yuan/month displayed risk ratios of 0. 470 [ 95％ CI ( 0.240, 0.920 ) ] and 0.281 [ 95％ CI ( 0.060 , 1.327 ) ], respectively; compared with patients with durations less than 5 vears, those with durations between 5 and 10 vears and with durations more than 10 vears displayed risk ratios of 1.644 [ 95％ CI ( 0.764, 3.536 ) ] and 3.246 [ 95％ CI ( 1.447, 7.283 ) ] respectively; compared with patients with HbA1c levels under 6.5％, those with HbA1c between 6.5％ and 7.5％ and with HbA1c levels above 7.5％ displayed risk ratios of 1.490 [ 95％ CI ( 0.653, 3.399 ) , 3.192 [ 95％ CI ( 1.562, 6.526 ) ] . Conclusion Income, HbA1c level, and length of duration are independent risk factors of DR. Early diagnosis, early treatment and blood glucose control are important to the prevention of DR pathogenesis, development, and blindness caused by DR.关键词
糖尿病,2型/糖尿病视网膜病变/社区/危险因素Key words
Diahetes mellitus, type2/ Diabetic retinopathy/ Community/ Risk Factors分类
医药卫生引用本文复制引用
张楠,袁申元,郑远远,万钢,吕玉洁,孙飞,卜祥雷,张译文,要立娜,马淑贤..社区糖尿病视网膜病变及危险因素探讨[J].中国全科医学,2011,14(26):2949-2952,4.基金项目
首都医学发展科研基金(2007-1035) （2007-1035）
