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伽玛刀治疗原发性肝癌对肝功能的影响研究

张江灵 陈少谊 陈云萍 郑维斌 赖灿辉

四川医学2011,Vol.32Issue(8):1214-1216,3.
四川医学2011,Vol.32Issue(8):1214-1216,3.

伽玛刀治疗原发性肝癌对肝功能的影响研究

Effect of gamma knife radiotherapy for primary hepatocellular carcinoma on liver function

张江灵 1陈少谊 1陈云萍 1郑维斌 1赖灿辉1

作者信息

  • 1. 解放军第180医院肿瘤科,福建,泉州,362000
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摘要

Abstract

Objective To study the effect of gamma knife radiotherapy for primary hepatocellular carcinoma on liver function. Methods To observe the variation of the Child-Pugh grade,blood clotting function and biochemical indexes on 67 patients who are cured by Gamma Knife after six months. Results After 3 months of which cured by gamma knife, the Child-Pugh grade raised . serologic ALB declined. PT, APTT and TT of blood clotting function prolength, and serologic ALT. AST and AKP raised.All of the indexes had statistic difference. Furthermore , 4 patiets had radioactive hepatic injury. The indexes of above-mentioned improved prominently after 6 months of cured by gamma knife radiotherapy. Conclution Hepatic injury which was treated by gamma knife radiotherapy was most serious after 3 months , but it recovered after 6 months. This study indicated that most of primary hepatocellular carcinoma patients' liver fuctions could tolerate by gamma knife radiotherapy so long as we know well of the indication.

关键词

肝肿瘤/放射治疗/肝损伤/伽玛刀

Key words

hepatocellular carcinoma/ radiational therapy / hepatic injury / gamma knife

分类

医药卫生

引用本文复制引用

张江灵,陈少谊,陈云萍,郑维斌,赖灿辉..伽玛刀治疗原发性肝癌对肝功能的影响研究[J].四川医学,2011,32(8):1214-1216,3.

四川医学

OACSTPCD

1004-0501

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