中国组织工程研究与临床康复2011，Vol.15Issue(38)：7193-7196,4.DOI:10.3969/j.issn.1673-8225.2011.38.039
缓释药物的研究进展及临床应用
Research progress and clinical application of sustained-release drugs
艾合买提江 1于永福 2黄相增3
作者信息
- 1. 新疆医科大学第六附属医院内一科,新疆维吾尔自治区乌鲁木齐市,830000
- 2. 新疆医科大学第五附属医院ICU科,新疆维吾尔自治区乌鲁木齐市,830011
- 3. 新疆医科大学第二附属医院内二科,新疆维吾尔自治区乌鲁木齐市,830028
- 折叠
摘要
Abstract
BACKGROUND: Currently, there are over 40 kinds of slow-release materials available for the production, which are widely usedin clinic.OBJECTIVE: To review several important drug carrier materials in the world as well as sustained-release drugs commonly used inclinic.METHODS: A computer search of CNKI and PubMed databases (2000-01/2010-12) were conducted for articles addressingsustained-release drugs. The keywords were “sustained release, drug, biomaterials” in Chinese and English. Meta analysis andrepetitive studies were excluded. Finally, 23 articles were included in result analysis.RESULTS AND CONCLUSION: Biodegradable synthetic polymer materials have become highly valued and widely used.Chitosan has become widely accepted for its good performance, as an important carrier of drug delivery; polylactic acid, abiodegradable polymer, plays an important treatment role in drug delivery; fibrin glue with high biocompatibility can effectivelydelay the drug release, which is widely used in many clinical areas.关键词
药物载体/缓释材料/生物降解/壳聚糖/纳米纤维/纤维蛋白分类
基础医学引用本文复制引用
艾合买提江,于永福,黄相增..缓释药物的研究进展及临床应用[J].中国组织工程研究与临床康复,2011,15(38):7193-7196,4.
