实用肝脏病杂志2011，Vol.14Issue(5)：336-337,2.DOI:10.3969/j.issn.1672-5069.2011.05.006
阿德福韦酯联合双环醇治疗慢性乙型肝炎患者临床观察
Clinical study on adefovir dipivoxil and bicyclol in treatment of patients with chronic hepatitis B
徐庆杰 1梁慧敏 1和振坤1
作者信息
- 1. 475000,河南省开封市,河南大学淮河医院感染病科
- 折叠
摘要
Abstract
Objective To explore adefovir dipivoxil and bicyclol in treating patients with chronic hepatitis B.Methods 62 patients with chronic hepatitis B were treated with adefovir dipivoxil and bicyclol for 96 weeks,and 60 were with adefovir dipivoxil for 96 weeks.Results At the end of the 96 week treatment,the ALT normalization rate in combination group was 96.8％,much higher than in control (80.0％,x2=5.8,P＜0.01) ;the HBeAg (41.9％ vs.33.3％,x2=2.1,P＞0.05)and HBV DNA loss (85.5％ vs.73.3％,x2=0.6,P＞0.05)in the two groups were not significantly different;the serum HA,LN,PC Ⅲ and Ⅳ-C levels in combination group decreased more obviouly than in control (P＜0.01).Conclusion Adefovir dipivoxil combined with bicyclol can improve liver function,and decrease serum markers of liver fibrosis.关键词
慢性乙型肝炎/阿德福韦酯/双环醇/治疗Key words
Hepatitis B/Adefovir dipivoxil/Bicyclol/Therapy引用本文复制引用
徐庆杰,梁慧敏,和振坤..阿德福韦酯联合双环醇治疗慢性乙型肝炎患者临床观察[J].实用肝脏病杂志,2011,14(5):336-337,2.
