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肝癌腹水癌细胞、白细胞体外抗癌药物敏感相关性研究

栗群英 彭燕 江忠勇 但刚 龚杨彬 熊杰

四川医学2011,Vol.32Issue(8):1291-1292,2.
四川医学2011,Vol.32Issue(8):1291-1292,2.

肝癌腹水癌细胞、白细胞体外抗癌药物敏感相关性研究

The study about the ralationship of anti-cancer drug sensitivity for heptoma cell and leukocyte

栗群英 1彭燕 1江忠勇 1但刚 1龚杨彬 1熊杰1

作者信息

  • 1. 成都军区总医院检验科,四川,成都,610083
  • 折叠

摘要

Abstract

Objective To investigate the clinic significance of 6 species anti-cancer drug susceptibility of which carcinoma cells and leukocyte in hydrogaster of advanced hepatoma. Methods CCK-8 is used to examine the cells inhibition which induced hy anti-cancer drugs. Results Inhibition of carcinoma cells from hydrogaster induced by carboplatin, cisplatin and adriamycin obviously stronger than leukocyte in many hepatoma( P < 0. 05) , the opposite results examined in hydroxycamptothecine in individual patients( P < 0. 05 ) , but the effection of mitomycin and fluorouracil on carcinoma cells and leukocyte was no difference ( P > 0. 05 ) . Conclusion To comparing the inhibition of 6 species anti-cancer drugs on carcinoma cells and leukocyte from advanced hepatoma, the high-performance anticancer drugs were determined as results of low toxicity for leukocyte and fetal for carcinoma cells. The study results will provide identify experiment data for optimizing chemotherapy plans and improving individual therapy popularizing clinic individual medication.

关键词

四甲基偶氮唑蓝比色法/癌细胞/白细胞/抗癌药敏

Key words

MTT/ carcinoma cells / leukocyte / sensitive of anticancer drugs

分类

医药卫生

引用本文复制引用

栗群英,彭燕,江忠勇,但刚,龚杨彬,熊杰..肝癌腹水癌细胞、白细胞体外抗癌药物敏感相关性研究[J].四川医学,2011,32(8):1291-1292,2.

四川医学

OACSTPCD

1004-0501

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