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离体肝切除联合自体肝移植大鼠模型的建立

刘文渊 张玉君 徐土炳 林恒 别平

山西医科大学学报2011,Vol.42Issue(9):703-705,3.
山西医科大学学报2011,Vol.42Issue(9):703-705,3.DOI:10.3969/J.ISSN.1007-6611.2011.09.002

离体肝切除联合自体肝移植大鼠模型的建立

Establishment of an extracorporeal liver resection and partial liver autotransplantation model in rats

刘文渊 1张玉君 2徐土炳 1林恒 1别平1

作者信息

  • 1. 第三军医大学西南医院全军肝胆外科研究所,重庆,400038
  • 2. 河北保定市66131部队卫生队
  • 折叠

摘要

Abstract

Objective To establish a stable rat model of extracorporeal liver resection and partial liver autotransplantation. Methods The rat model of extracorporeal liver resection and partial liver autotransplantation was established by continuous suturing for the hepatic vena cava and portal vein anastomosis, bile duct reconstruction using stents, and liver resection without damage. Results The anhepatic time was ( 20.14 ± 1.53 )min. The survival rate was 91.7% after operation,and one week survival rate was 80%. Conclusion The rat model of extracorporeal liver resection and partial liver autotransplantation can be used as a reliable and stable experimental model with the high survival rate and repeatability.

关键词

离体肝切除/自体肝移植/大鼠

Key words

extracorporeal liver resection/ partial liver autotransplantation/ rats

分类

医药卫生

引用本文复制引用

刘文渊,张玉君,徐土炳,林恒,别平..离体肝切除联合自体肝移植大鼠模型的建立[J].山西医科大学学报,2011,42(9):703-705,3.

基金项目

国家自然科学基金资助项目(30872494) (30872494)

山西医科大学学报

OACSTPCD

1007-6611

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