中国妇幼健康研究2011，Vol.22Issue(5)：705-708,4.DOI:10.3969/j.issn.1673-5293.2011.05.057
蜕膜自然杀伤细胞受体与自然流产研究进展
Progress in study on decidual natural killer cell receptors and spontaneous abortion
卞寿芳 1马庆良1
作者信息
- 1. 上海交通大学医学院附属仁济医院妇产科,上海,200001
- 折叠
摘要
Abstract
Physiological process of human pregnancy is extremely complicated, and decidual natural killer ( dNK ) cells are the most important decidual lymphocytes in early pregnancy. The function of dNK cells is different from the peripheral blood natural killer ( PBNK )cells. They participate in the deciduas developing, recasting uterine blood vessels and regulating maternal-fetal immune balance. Decidual NK cells express many kinds of inhibitory and activating receptors, which can bind with major histocompatibility complex or non-major histocompatibility complex ligand, and regulate NK cells in inhibited or activated state. The defect of the NK cells may lead to pathological pregnancy occurrence such as recurrent abortion.关键词
蜕膜自然杀伤细胞/活化性受体/复发性流产/免疫球蛋白样受体Key words
decidual natural killer ( dNK ) cell /activating receptor/ recurrent abortion/immunoglobulin-like receptor分类
医药卫生引用本文复制引用
卞寿芳,马庆良..蜕膜自然杀伤细胞受体与自然流产研究进展[J].中国妇幼健康研究,2011,22(5):705-708,4.
