中国妇幼健康研究2011，Vol.22Issue(5)：623-624,627,3.DOI:10.3969/j.issn.1673-5293.2011.05.021
川崎病54例临床诊治分析
Clinical analysis of 54 cases with kawasaki disease
刘永林 1张在义1
作者信息
- 1. 陕西省神木县医院儿科,陕西,神木,719300
- 折叠
摘要
Abstract
Objective To investigate the clinical features of kawasaki disease ( KD ) and coronary arter lesions. Methods The data of 54 cases of KD admitted in pediatric department of Shenmu County Hospital from August 1999 to December 2010 was retrospectively analyzed.Results Among 54 cases of KD, 38 were males and 16 were females, and the male to female ratio was 2.37:1. The age of them ranged from 2 months to 8 years, with an average onset age of 3 years and 2 months. There were 14 cases younger than one year, 14 between 1 and 3 years old, 12 between 3 and 5 years and 14 older than 5 years. Among the cases in the study, 38 were typical and 16 were atypical.There were 24 cases with coronary artery lesions, 20 cases with expansion of coronary artery, 4 cases with coronary artery anemrysm ( CAA )and 4 cases with pericardial effusion. They were followed up for 6 months to 2 years. Coronary arter recovered within 12 months after treatment. Two cases relapsed one year later. Conclusion The incidence of coronary artery lesions was high ( 44.4％ ), which was related with late diagnosis, more atypical cases, poor medical conditions of the county hospital and not application of intravenous gammaglobulin timely. Application of a single dose ( 1.0-2.0g/kg ) of intravenous gammaglobulin within 10 days is better than 400 mg · kg-1 · d-1 therapy for fever relieving and coronary artery lesions. Attention should be paid to BCG scar redness and swelling, perianal desquamations,ESR and C-reactive protein ( CRP ) increasing in atypical cases.关键词
川崎病/不典型川崎病/冠状动脉损害/人血丙种球蛋白Key words
Kawasaki disease ( KD )/atypical kawasaki disease/coronary artery lesions/gammaglobulin分类
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刘永林,张在义..川崎病54例临床诊治分析[J].中国妇幼健康研究,2011,22(5):623-624,627,3.
