替罗非班对急性ST段抬高型心肌梗死并糖尿病患者急诊经皮冠状动脉介入治疗术后血清MMP-9水平的影响及临床意义OACSCDCSTPCD
Effect and clinical significance of tirofiban on serum matrix metalloproteinase 9 after primary percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction and diabetes
目的:探讨替罗非班对急性ST段抬高型心肌梗死(STEMI)并糖尿病患者急诊经皮冠状动脉介入治疗(PCI)术后血清基质金属蛋白酶-9(MMP-9)水平的影响及临床意义.方法:急诊PCI治疗的STEMI并糖尿病患者123例,分为常规治疗组61例和替罗非班组62例.分别比较两组患者一般临床资料及冠状动脉病变情况,比较两组患者急诊PCI术前及术后的血清MMP-9水平,比较两组患者在PCI术后12个月冠状动脉支架内再狭窄的发生率.结果:两组患者一般临床资料…查看全部>>
AIM: To study the effect and clinical significance of tirofiban on serum matrix metalloproteinase 9 (MMP-9) and after primary percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI) and diabetes. METHODS: One hundred and twenty-three patients with acute STEMI and diabetes who were treated with primary PCI were designed into two groups: routine treatment group(61 cases) and tirofiban group(62cases). T…查看全部>>
邓少雄;郭南鸥;郑渊;黄文森
福建省泉州医学高等专科学校内科教研室,泉州,362000,福建福建医科大学附属泉州市第一医院心内科,泉州,362000,福建福建省泉州医学高等专科学校内科教研室,泉州,362000,福建福建省泉州医学高等专科学校内科教研室,泉州,362000,福建
医药卫生
替罗非班心肌梗死糖尿病经皮冠状动脉介入治疗基质金属蛋白酶-9
TirofibanMyocardial infarctionDiabetes Primary percutaneous coronary intervention Matrix metalloproteinase-9
《中国临床药理学与治疗学》 2011 (7)
807-811,5
泉州市科技局基金资助项目(2007251)
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