广东医学2011，Vol.32Issue(16)：2209-2211,3.
中医心身同治方案治疗绝经综合征抑郁症状的随机对照研究
Randomized controlled study of depressive symptoms in postmenopausal women using traditional Chinese medicines based on the regimen of psychosomatic mutual aid treatment. YANG Hong -yan*, WANG Xiao -yun, XU
摘要
Abstract
Objective To evaluate the efficacy and safety of traditional Chinese medicines based on the regimen of psychosomatic mutual aid treatment and treatment with Tibolone tablets plus psychological intervention in treatment of depressive symptoms in postmenopausal women. Methods Sixty patients with menopausal decompression syndromes were embed and randomized into two groups: the experiment group ( using Chinese medicines plus Chinese psychosomatic mumai aid treatment) and the control group ( using Tibolone tablets plus psychological intervention). The relative placebos of Chinese Medicines and Tibolone tablets were given accordingly. The study was composed with 8 week treatment and the 4 week follow - up. Kupperman Index (KI) and self - rating depression scale (SDS) were adopted as the final evaluation standards. The side effects were also evaluated using experimental parameters. Therapeutic efficacy and side effects were assessed at baseline, 4th and 8th week during treatment, and during the follow - up. Results Somatic symptoms and mild to moderate depression symptoms were alleviated in both groups, without significant difference. The beneficial effects continued in the experiment group, although rebound occurred in the control group during the follow -up. There was no side effect recorded in the experiment group. However, 9 cases in the control group were reported with side effects. Conelusion Chinese medicines based on the regimen of psychosomatic mutual aid treatment shows stable, continuous and safe therapeutic effects on the menopausal syndrome with mild to moderate depression symptoms.关键词
绝经综合征/中医心身同治/随机对照试验Key words
menopausal syndrome/ Chinese psychosomatic mutual aid treatment/ randomized controlled trial引用本文复制引用
杨洪艳,王小云,许英,温泽淮,张春玲,聂广宁,成芳平..中医心身同治方案治疗绝经综合征抑郁症状的随机对照研究[J].广东医学,2011,32(16):2209-2211,3.基金项目
国家"十一五"科技支撑计划项目(编号:2007BAI20B014) （编号:2007BAI20B014）
