摘要
Abstract
Objective To observe the change of P-wave dispersion (Pdisp) and myocardial enzymes in the patients with acute intracerebral hemorrhage (AICH), and to explore the characteristics of myocardial damage.Methods Two-hundred and twenty-seven AICH patients were enrolled.The electrocardiogram was examined within 24-hour (24h) and on the seventh day (7d) after admission.The maximum P-wave timing (Pmax) and minimum P-wave timing (Pmin) were measured, and the Pdisp was calculated.The patients were divided into three groups according to the Glasgow scale, including the mild (13-15scores), moderate (9-12 scores) and severe group (3-8 scores).The blood myocardial enzymes,including lactate dehydrogenase (LDH), alpha-hydroxybutyrate dehydrogenase (α-HBDH), creatine kinase (CK), and MB isoenzyme of creatine kinase (CK-MB) were examined within 24h and compared among the three groups.Results The Pmin within 24h had no difference with that on the 7d (P=0.710).However, the AICH patients showed significantly more prolonged Pmax (P=0.002) and Pdisp (P=0.006) within 24h than that on the 7d.The positive number of Pmax more than ll0ms was significantly higher within 24h (19.8％) than that on the 7d (5.7％, P＜0.01).Similarly, the positive number of Pdisp more than 40ms was also higher within 24h (67.4％) than that on the 7d (58.1％, P=0.041).It showed marked differences in myocardial enzymes among the three groups (P＜0.01).CK, CK-MB, LDH and α-HBDH in severe group were obviously higher than that of moderate and mild groups (P＜0.01).The cardiac enzymes in moderate group were also higher than that of mild group (P＜0.01).Conclusion The myocardial damage existed in AICH patients with different degrees; it was closely related to the severe degree of the AICH.关键词
脑出血；心肌缺血；心电描记术；肌酸激酶；肌酸激酶，MB；L-乳酸脱氢酶；羟丁酸脱氢酶Key words
Cerebral hemorrhage/ Myocardial ischemia/ Electrocardiography/ Creatine kinase/Creatine kinase, MB form/ L-lactate dehydrogenase/ L-lactate dehydrogenase
