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市售4种有机磷农药急性毒性研究

李鹏 尹雅玲 王倩倩 赵繁荣 潘国聘 张玉林

安徽农业科学2011,Vol.39Issue(19):11526-11528,3.
安徽农业科学2011,Vol.39Issue(19):11526-11528,3.

市售4种有机磷农药急性毒性研究

Study on Acute Toxicity of 4 Commercial Organophosphorus Pesticides

李鹏 1尹雅玲 2王倩倩 1赵繁荣 1潘国聘 1张玉林1

作者信息

  • 1. 新乡医学院药学院,河南,新乡,453003
  • 2. 新乡医学院基础医学院,河南,新乡,453003
  • 折叠

摘要

Abstract

[ Objective ] The study aimed to detect the acute toxicity of 4 commercial organophosphorus pesticides to SD rat. [ Method ] With 4 - 5 month-old and 180 - 220 kg weighted male SD rats at clean level as the tested animals, their stomaches were peffused with 4 kinds of organophosphorus pesticides at different quality concn. The poisoning performance of the SD rats was observed and their death time was recorded. The acute toxigenicity effect characteristics, the toxigenicity effects between the pesticides and their security concn. were evaluated and their reasons were analyzed. [Result] The lethal concn. (LC50) in 24, 48, 72 and 96 h to SD rat were 3.892, 3.051, 2.618 and 2.458 g/kg resp. for phoxim; that were 0.015, 0.013, 0.012 and 0.011 g/kg resp. for isofenphos-methyl; that were 0. 049, 0.046, 0.043 and 0. 041 g/kg resp. for isocarbophos; that were 0. 137, 0.113, 0. 100 and 0.085 g/kg resp. for acephate. [ Conclusion] 4 kinds of organophosphorus pesticides showed the acute toxicity effect with the cumulative toxicity as the main and their toxicity to the SD rat was in order of isofenphos-methyl > isocarbophos > acephate > phoxim.

关键词

辛硫磷/乙酰甲胺磷/甲基异柳磷/水胺硫磷/急性毒性/SD大鼠

Key words

Phoxim/ Acephate/ lsofenphos-methyl/ Isocarbophos/ Acute toxicity/ SD rat

分类

农业科技

引用本文复制引用

李鹏,尹雅玲,王倩倩,赵繁荣,潘国聘,张玉林..市售4种有机磷农药急性毒性研究[J].安徽农业科学,2011,39(19):11526-11528,3.

基金项目

河南省教育厅2010年度自然科学研究计划项目(2010B320011). (2010B320011)

安徽农业科学

0517-6611

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