中国药业2011,Vol.20Issue(19):7-8,2.
昆布多糖对家兔血小板聚集和释放的影响
Effect of Thallus Laminariae Polysaccharides on Platelet Aggregation and Release Reaction in Rabbits
摘要
Abstract
Objective To investigate the effect of thallus laminariae polysaccharides(TLP) on platelet aggregation and release reaction in rabbits. Methods We observed the effect of TLP on platelet aggregation which was induced by PAF in rabbits in vivo study, using turbidimetry, and determined GMP- 140 in plasma using double antibody sandwich method. Results Compared with the saline group,TLP inhibited PAF-induced platelet aggregation were significantly different(P<0.05, P<0.01),and can reduce the content of GMP- 140( P <0.01 ). Conclusion TLP could resistant PAF-induced platelet aggregation and release,关键词
昆布多糖/抗血小板聚集/二磷酸腺苷/血小板颗粒膜蛋白Key words
TLP/ anti - platelet aggregation/ ADP/ GMP - 140分类
医药卫生引用本文复制引用
曾惠芬,徐露..昆布多糖对家兔血小板聚集和释放的影响[J].中国药业,2011,20(19):7-8,2.基金项目
广东省中山市医学科学技术研究基镏金,项目编号:2010102. ()