重庆医学2011,Vol.40Issue(30):3053-3055,3.DOI:10.3969/j.issn.1671-8348.2011.30.016
血液病患者血小板计数与院内感染发生的关系研究
Relationship between the platelet counts and nosocomial infection in patients with hematologic disease
刘静 1王小中 1李静 2黄波 1肖芸 1熊火梅 1章海斌 1冯丹琴 1陈希敏1
作者信息
- 1. 南昌大学第二附属医院检验科,江西南昌,330006
- 2. 南昌大学第一附属医院检验科,江西南昌,330006
- 折叠
摘要
Abstract
Objective To investigate the relationship between platelet counts and nosocomial infection in patients with hematologic disease. Methods Parameters of PLT in 311 nosocomial infected patients with hematologic disease were analyzed retrospectively. The relationship between the platelet counts and nosocomial infection was observed. Results The total infection rate of he matologic disease in patients was 9.27%. A total of 311 pathogens were isolated by bacterial culture,in which the major pathogenic bacteria were the Gram-negative bacilli (200 strains, 64.3 %) ,the Gram positive bacteria were 28.3 % (88 strains) and fungi were 7.4 % (23 strains). The most common infection included pulmonary infection (ll7cases, 37. 6%), blood infection (81 cases,26.0 %), and nasopharyngeal infection (80 cases, 25.7% ). The platelet count of infected group was significantly lower than that in the non-infected group and the overall level (both P=0). In addition,the platelet count was inversely proportional to the infection rate. The platelet counts of patients with pharyngeal mucosal infection and blood infection were also significantly lower than that in the patients with lung infection and the overall level (both P<0.05). Conclusion The platelet count could be considered as a useful factor for infection prevention in patients with hematologic disease, who undergo nosocomial infection.关键词
血小板计数/交叉感染/血液病Key words
platelet count/ cross infection/ hematologic diseases引用本文复制引用
刘静,王小中,李静,黄波,肖芸,熊火梅,章海斌,冯丹琴,陈希敏..血液病患者血小板计数与院内感染发生的关系研究[J].重庆医学,2011,40(30):3053-3055,3.