中国全科医学2011,Vol.14Issue(29):3362-3363,3366,3.
慢性心力衰竭患者血清白介素6、高敏C反应蛋白和肿瘤坏死因子α水平的变化及临床意义
Serum Concentrations of IL-6,Hs-CRP and TNF-α in Patients with Chronic Cardiac Failure and the Clinical Significance
朱海霞1
作者信息
- 1. 010050,内蒙古呼和浩特市,内蒙古医学院第一附属医院康复科
- 折叠
摘要
Abstract
Objective To explore the serum concentrations of IL - 6, Hs - CRP and TNF - a in patients with chronic heart failure and the clinical significance. Methods Serum concentrations of IL -6 ,Hs - CRP and TNF - a in 38 healthy volunteers ( control group ) and 95 patients with chronic heart failure were determined. Ejection fraction and mass index of left ventricle were measured by echocardiography. Results Serum concentrations of IL - 6, Hs - CRP and TNF - a in patients with different chronic heart failure were significantly different from those of the control group ( P < 0. 01 ). Serum concentrations of IL - 6, Hs - CRP and TNF - a were positively related to NYHA grading and the mass index of left ventricle and negatively related to ejection fraction of left ventricle( P <0. 01 ). Conclusion Serum concentrations of IL - 6,Hs - CRP and TNF - a can be used as indicators of left ventricle heart failure indicators and can be ancillary used in the diagnosis of chronic heart failure.关键词
心力衰竭/白介素6/C反应蛋白/肿瘤坏死因子αKey words
Heart failure/ Interleukin - 6/ C - reactive protein/ Tumor necrosis factor - alpha分类
医药卫生引用本文复制引用
朱海霞..慢性心力衰竭患者血清白介素6、高敏C反应蛋白和肿瘤坏死因子α水平的变化及临床意义[J].中国全科医学,2011,14(29):3362-3363,3366,3.