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骨髓单个核细胞移植结合髓芯减压治疗早期股骨头坏死的三维步态分析

赵德伟 谢辉 崔大平

中国组织工程研究与临床康复2011,Vol.15Issue(32):5999-6002,4.
中国组织工程研究与临床康复2011,Vol.15Issue(32):5999-6002,4.DOI:10.3969/j.issn.1673-8225.2011.32.025

骨髓单个核细胞移植结合髓芯减压治疗早期股骨头坏死的三维步态分析

Bone marrow mononuclear cell transplantation combined with core decompression treatment for early osteonecrosis: A three-dimensional gait analysis

赵德伟 1谢辉 2崔大平1

作者信息

  • 1. 大连大学附属中山医院,辽宁省大连市,116001
  • 2. 大连大学研究生院,辽宁省大连市,116001
  • 折叠

摘要

Abstract

BACKGROUND: Gait analysis provides an objective and accurate quantitative assessment for the orthopedic examination. OBJECTIVE: To observe the gait kinematic characteristics and change rule of patients with early avascular necrosis of the femoral head following treatment of bone marrow mononuclear cell (BMMCs) transplantation combined with core decompression treatment. METHODS: Three-dimensional motion capture gait analysis was performed in 21 cases of early osteonecrosis undergoing BMMCs transplantation with core decompression. Before and 3, 6, 9, 12 months after treatment, step length, step width, angle of hip motion, kinematic data of hip angle acceleration in the 22 patients walking on the treadmill of 0° and 15°. Gait data of 33 healthy subjects were collected for comparison. RESULTS AND CONCLUSION: Three months after treatment, 21 patients presented with reduced pain gait. The spatial-temporal parameters had no difference from normal people at 3 months for treadmill movement of 0° and 6 months for treadmill movement of 15°. At 9 months, kinematic indexes for 15° inclined treadmill movement were consistent with the normal. The findings indicated that BMMSCs for necrosis of the femoral head can recover normal gait mode of the hip in a time-dependent manner.

关键词

步态分析/股骨头坏死/三维运动学/髓芯减压/干细胞回植

分类

医药卫生

引用本文复制引用

赵德伟,谢辉,崔大平..骨髓单个核细胞移植结合髓芯减压治疗早期股骨头坏死的三维步态分析[J].中国组织工程研究与临床康复,2011,15(32):5999-6002,4.

中国组织工程研究与临床康复

OACSCDCSTPCD

2095-4344

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