中国药业2011，Vol.20Issue(20)：36-37,2.
总有机碳法检测设备清洁时乌苯美司的残留量
Study on TOC Method to Determine Ubenimex Residual in Pharmaceutical Equipments Cleaning
蔡旭萍 1吴彩萍 1赵爱桔 2葛孝忠1
作者信息
- 1. 浙江普洛康裕制药有限公司,浙江,东阳,322118
- 2. 浙江省医药经济发展中心,浙江,杭州,310012
- 折叠
摘要
Abstract
Objective To establish a method for determining ubenimex residual in pharmaceutical equipments cleaning. Methods The con-tent of ubenimex residual was determined by total organic carbon (TOC) method and calculated by external standard method. Results There was a good linear relationship between the ubenimex concentration and the peak area in the range of 1-12 μg/mL( r = 0. 999 9). The minimum detectable limit was 0.16 μg/mL The average recovery rate was 82. 5%, RSD 10. 4%. Conclusion This method is simple, rapid, ac-curate and specific, which can be used for the determination of ubenimex residual in pharmaceutical equipments cleaning.关键词
设备清洁/鸟笨美司/残留量/总有机碳Key words
pharmaceutical equipments cleaning/ ubenimex/ residual/ total organic carbon分类
化学化工引用本文复制引用
蔡旭萍,吴彩萍,赵爱桔,葛孝忠..总有机碳法检测设备清洁时乌苯美司的残留量[J].中国药业,2011,20(20):36-37,2.
