中国病理生理杂志2011，Vol.27Issue(10)：2024-2026,3.DOI:10.3969/j.issn.1000-4718.2011.10.033
微管相关蛋白2、巢蛋白与人胚胎食管肌层发育的关系
Relationship between MAP-2, nestin and development of muscular layer of human embryonic esophagus
摘要
Abstract
AIM: To explore the relationship between microtubule - associated protein 2 ( MAP - 2 ), nestin and development of esophageal muscular layer in human embryos. METHODS: At the second to fourth month of gestation, the protein expression of MAP - 2 and nestin was observed using the PV method of immunohistochemistry in the human embryonic esophageal tissues. RESULTS: At the second month, the third month and the fourth month of gestation, MAP -2 positive expression in the neural cells of the intermuscular nerve plexus, and negative expression in the muscle cells of human embryonic developing esophageal muscle were observed. Nestin positive expression was found in the muscle cells at the second month to the third month of gestation. However, no nestin expression in the muscle cells of the esophageal muscle at the fourth month of gestation was observed. At the second month to the fourth month of gestation, nestin showed negative or weak positive expression in the neural cells of the intermuscular nerve plexus of human embryonic esophageal tissues. CONCLUSION: MAP - 2 and nestin might regulate the formation of esophageal muscular layer in human embryos.关键词
食管/微管相关蛋白2/巢蛋白/人胚胎Key words
Esophagus/Microtubule - associated protein 2/Nestin/Human embryo分类
管理科学引用本文复制引用
张泳,刘学红..微管相关蛋白2、巢蛋白与人胚胎食管肌层发育的关系[J].中国病理生理杂志,2011,27(10):2024-2026,3.基金项目
浙江省教育厅科研计划资助项目(No.Y201018535) （No.Y201018535）
绍兴文理学院重点项目(No.2010LG1011) （No.2010LG1011）
