中医药导报2011，Vol.17Issue(10)：25-28,4.
楂葛降脂袋泡茶剂对非酒精性脂肪肝大鼠肝脏形态学改变的影响
The effect of Zhage reduced-fat teabags on morphological changes of the experimental nonalcoholic fatty liver disease in rats
摘要
Abstract
Objective To eplore the effect of Zhage reduced-fat teabags(ZhaGe) On morphological changes of the experimental nonalcoholic fatty liver disease in rats and provide the experimental basis for the clinical therapy of nonalcoholic fatty liver disease. Methods The animal model of fatty liver was duplicated with high fat diet and was randomly divided into model group, Lipid-lowering tongluo soft capsule group, high dose ZhaGe group, middle dose ZhaGe group, low dose ZhaGe group, and normal control group. All the treatment groups were intervened by its own medicine. Liver tissue was extracted and made HE staining, then observed by optical microscope. Results Model group are visible diffuse hepatic steatosis, mainly for the big bubble sex steatosis, some small bubble sex steatosis, and note the amount of inflammatory cells infiltrating; ZhaGe group for normal liver tissue. At higher magnification, only a small amount of liver cells have small empty bubble kind change.Conclusion Zhage reduced-fat teabags to nonalcoholic fatty liver disease sex has good prevention and treatment effect. But in the certain degree to prevent liver fat deposition, improve liver function, excessive improve hepatic steatosis, reduce the liver tissue inflammation.关键词
非酒精性脂肪肝/楂葛降脂袋泡茶剂/大鼠/肝组织/病理组织学Key words
Nonalcoholic fatty liver disease/ Zhage reduced-fat teabags/ Rats/ Liver tissue/ Pathological histologic分类
医药卫生引用本文复制引用
黄孟君,曹永常,周薪蓓,余敏,李俊贤,姚军,余红运..楂葛降脂袋泡茶剂对非酒精性脂肪肝大鼠肝脏形态学改变的影响[J].中医药导报,2011,17(10):25-28,4.基金项目
湖南省研究生科研创新基金项目(CX2010B352) （CX2010B352）
