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Nanog在大鼠心肌梗死后组织表达的变化

吕风华 高建芝 滕清雷 郭志坤

实用医学杂志2011,Vol.27Issue(16):2929-2931,3.
实用医学杂志2011,Vol.27Issue(16):2929-2931,3.DOI:10.3969/j.issn.1006-5725.2011.16.017

Nanog在大鼠心肌梗死后组织表达的变化

Change of nanog protein in rat's cardiac tissues after myocardial infarction

吕风华 1高建芝 2滕清雷 3郭志坤4

作者信息

  • 1. 453100,新乡医学院第一附属医院心内一科
  • 2. 453003,新乡医学院基础医学院
  • 3. 453000,新乡医学院第三附属医院麻醉科
  • 4. 453003,新乡医学院河南省组织再生重点实验室
  • 折叠

摘要

Abstract

Objective To provide morphological evidences for clinical therapy and research of acute myocardial ischemic by investigating the change of nanog's expression in cardiac tissue after myocardial infarction in rats. Methods Twenty SD healthy male rats were randomized into myocardial ischemic group (model group, n = 10) and sham operation group (re = 10). Expression of nanog protein in rats' cardiac tissue was measured by immunofluorescence and Western blot. Results Immunofluorescence results showed that nanog protein was negatively expressed in sham group, while that was weakly expressed in model group. Weatern blot results showed that the expression of nanog protein in model group was significantly higher than that in sham group (P < 0.05). Conclusion Nanog peotein may play a role in the post-ischemia myocardium repairing.

关键词

Nanog/心肌修复/免疫荧光/Western blot

Key words

Nanog/Myocardial infarction /Immunofluorescence /Western blot

引用本文复制引用

吕风华,高建芝,滕清雷,郭志坤..Nanog在大鼠心肌梗死后组织表达的变化[J].实用医学杂志,2011,27(16):2929-2931,3.

基金项目

河南省杰出创新人才基金(编号:HNlFOS2006023) (编号:HNlFOS2006023)

实用医学杂志

OA北大核心CSTPCD

1006-5725

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