实用医学杂志2011,Vol.27Issue(16):2929-2931,3.DOI:10.3969/j.issn.1006-5725.2011.16.017
Nanog在大鼠心肌梗死后组织表达的变化
Change of nanog protein in rat's cardiac tissues after myocardial infarction
摘要
Abstract
Objective To provide morphological evidences for clinical therapy and research of acute myocardial ischemic by investigating the change of nanog's expression in cardiac tissue after myocardial infarction in rats. Methods Twenty SD healthy male rats were randomized into myocardial ischemic group (model group, n = 10) and sham operation group (re = 10). Expression of nanog protein in rats' cardiac tissue was measured by immunofluorescence and Western blot. Results Immunofluorescence results showed that nanog protein was negatively expressed in sham group, while that was weakly expressed in model group. Weatern blot results showed that the expression of nanog protein in model group was significantly higher than that in sham group (P < 0.05). Conclusion Nanog peotein may play a role in the post-ischemia myocardium repairing.关键词
Nanog/心肌修复/免疫荧光/Western blotKey words
Nanog/Myocardial infarction /Immunofluorescence /Western blot引用本文复制引用
吕风华,高建芝,滕清雷,郭志坤..Nanog在大鼠心肌梗死后组织表达的变化[J].实用医学杂志,2011,27(16):2929-2931,3.基金项目
河南省杰出创新人才基金(编号:HNlFOS2006023) (编号:HNlFOS2006023)