针灸临床杂志2011，Vol.27Issue(6)：75-78,4.
电项针对大鼠睡眠剥夺诱发氧化应激反应影响机制研究
The Effect of Electro-nape-acupuncture on the Mechanism of Rats' Oxidative Stress Reaction Induced by sleep Deprivation
摘要
Abstract
Objective;To discuss the mechanism of the electro - nape - acupuncture on the effect of rats of sleep deprivation and oxidative stress induced by it through the intervention of sleep deprivation experiments on rats. Methods: Rats were randomly divided into control group, model group, the acupuncture group, and astragalus injection group. In addition to the control group,other groups were duplicated of sleep deprivation rats models by intraperitoneal injection of PCPA. Observe the content of NO and SOD by grating spectrophotometer method. Results: Confirmed by grating spectrophotometer method, the electro - nape - acupuncture and astragalus injection could decrease the contents of NO and SOD in the brainstem reticular of the sleep deprivation rats. Compared with the model group, there were significant differences (P <0. 01). Compared with one another, the difference was no significant (P >0.05). Observe by electron microscopy, in the model group the borders of cells in brain stem of rats was not clear, mitochondria degenerated clearly, the contents of rough endoplasmic reticulum decreased, synaptic integrated, the cells of rats in the electro - nape - acupuncture group did not change significantly. Conclusion: Electro - nape - acupuncture can reduce the oxidative stress response, and neurotoxicity can be decreased among sleep deprivation rats through electro - nape - acupuncture..关键词
电项针/睡眠剥夺/氧化应激/实验研究Key words
Electro-nape-acupuncture/ Sleep deprivation/ Oxidative stress Experimental research分类
医药卫生引用本文复制引用
吴北峰,黄日龙,彭艳..电项针对大鼠睡眠剥夺诱发氧化应激反应影响机制研究[J].针灸临床杂志,2011,27(6):75-78,4.基金项目
黑龙江省中医药管理局课题，编号：ZHY08-W50。 （）
