现代检验医学杂志2011，Vol.26Issue(5)：137-138,2.DOI:10.3969/j.issn.1671-7414.2011.05.048
抗Ro-52抗体与抗SSA抗体在自身免疫病中的检测意义
Significance of Anti-Ro-52 kDa and SSA Antibodies in Patients with Autoimmune Diseases
摘要
Abstract
Objective To investigate the clinical correlation of anti-Ro-52 and SSA antibody and to determine the clinical diagnostic value of anti-Ro-52/SSA in Chinese patients presenting with SLE,SS and other autoimmune diseases. Methods Serum samples from 50 patients with SLE, 50 with SS and 30 other autoimmune diseases were tested for the presence of anti-Ro-52 and anti-SSA using a commercial WB kit, AN A were tested by IIF,50 health people serum as controls. Results The positive rate of anti-Ro-52 and SSA in patients with SLE were 60% and 64% respectively,patients with SS were 72% and 82% respectively,patients with other autoimmune diseases were 30% and 23. 33% respectively,higher than control group (6%),and with X2 inspection,the difference was statistically significant (P<0. 05). Conclusion High prevalence of anti-Ro-52 and SSA is of significance in diagnosis of SLE and SS,the relationship between the two needs to be further explored.关键词
系统性红斑狼疮/舍格伦综合症/自身抗体/抗Ro-52抗体Key words
systemic lupus erythematosus(SLE)/sjδgren's syndrome(SS)/autoantibody/anti-Ro-52分类
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金燕萍,林贵高,阎超,鄢盛恺..抗Ro-52抗体与抗SSA抗体在自身免疫病中的检测意义[J].现代检验医学杂志,2011,26(5):137-138,2.
