现代检验医学杂志2011,Vol.26Issue(5):139-141,144,4.DOI:10.3969/j.issn.1671-7414.2011.05.049
侵袭性大颗粒淋巴细胞白血病MICM诊断及临床特征分析
MICM Characteristie and Clinical Analysis of the Aggressive Large Lymphocytic Leukemia(LGLL)
翟洪顺 1林丽淑 2邹德学 1聂李平 1刘延涛 3周宇 1张莉莉1
作者信息
- 1. 北京大学深圳医院检验科,广东深圳,518036
- 2. 深圳福田第二人民医院检验科,广东深圳,518036
- 3. 深圳阳光医院检验科,广东深圳,518008
- 折叠
摘要
Abstract
Objective To improve and analyse the diagnose level of large granular lymphocyte leukemia (LGLL). Methods To report 3 cases of patients with aggressive LGLL had found and the review of literature. Results 1 case of T-LGLL and 2 cases of NK-LGLL had aggressive process,their clinical characters were obviously general symptom.hepatomegaly, splenomegaly.these disease develop quickly and had bad prognosis. The immunophenotype had unique feature.Lymphocyte morphology feature and CE,ACP and PAS of Lymphocyte in LGLL patient was the important diagnose clue. Conclusion As a group of heterogeneous disease,the summary diagnose of LGLL should be based on clinical manifestation .lymphocyte morphology feature and immunophenotype and differentiated it carefully.关键词
大颗粒淋巴细胞白血病/异质性/临床分析/MICMKey words
large granular lymphocytic leukemia/heterogeneous!clinical analysis/MICM分类
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翟洪顺,林丽淑,邹德学,聂李平,刘延涛,周宇,张莉莉..侵袭性大颗粒淋巴细胞白血病MICM诊断及临床特征分析[J].现代检验医学杂志,2011,26(5):139-141,144,4.