重庆医学2011，Vol.40Issue(29)：2922-2924,3.DOI:10.3969/j.issn.1671-8348.2011.29.004
贵州省新发现HIV-1毒株亚型特征研究
The Study of characteristic of new HIV-1 subtypes in Guizhou
摘要
Abstract
Objective To study the HIV-1 subtype strain distribution and epidemic characteristics in Guizhou province and to provide scientific data for HIV/AIDS prevention and control. Methods Using a nested Polymerase Chain Reaction(PCR)to amplify gag and env gene of HIV strains,and for sequencing. Results 119 samples were amplified and sequenced successfully among 128 samples,of which 62 subtype CRF01-AE,49 recombinant subtype CRF07-BC,2 recombinant subtype CRF08-BC and 6 subtype B. Conclusion The study showed that newly discovered recombinant subtype CRF01-AE was most prevalent in Guizhou province, recombinant subtype CRF07-BC was the second one. Different subtypes of HIV stains existed. The results suggest that the subtypes of HIVstains will change to sexual transmission.关键词
HIV-1/亚型特征/基因Key words
HIV-1/ characteristics genotype/genes引用本文复制引用
孙显光,何翔,李志坚,张信辉,申莉梅..贵州省新发现HIV-1毒株亚型特征研究[J].重庆医学,2011,40(29):2922-2924,3.基金项目
贵州省"十一五"重点攻关社发资金项目(黔科合NY字[2006]-3051). （黔科合NY字[2006]-3051）
