中国组织工程研究与临床康复2011，Vol.15Issue(32)：5936-5940,5.DOI:10.3969/j.issn.1673-8225.2011.32.011
脂肪与骨髓来源间充质干细胞生物学特性的比较
Comparison of the biological characteristics of bone marrow and adipose tissue derived mesenchymal stem cells
朱希山 1施薇 1台卫平 1安广宇1
作者信息
- 1. 首都医科大学附属北京世纪坛医院(北京大学第九临床医学院)肿瘤内科,北京市,100038
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摘要
Abstract
BACKGROUND: Recently, adipose tissue derived mesenchymal stem cells due to easy to be harvested have been widely studied. OBJECTIVE: To compare the biological characteristics of adipose tissue derived mesenchymal stem cells and bone marrow mesenchymal stem cells. METHODS: Adipose tissue derived mesenchymal stem cells and bone marrow mesenchymal stem cells were isolated and cultured in vitro to compare their phenotype, cell doubling time and the level of secreted factors. RESULTS AND CONCLUSION: Adipose tissue derived mesenchymal stem cells have similar phenotype and differentiation ability as bone marrow mesenchymal stem cells except CD106 expression. The frequency of mesenchymal stem cells in bone marrow and adipose tissue was also calculated and found that mesenchymal stem cells frequency in adipose tissue was 10 times higher than bone marrow. This result can be an instruction for mesenchymal stem cells clinical use.关键词
脂肪间充质干细胞/骨髓间充质干细胞/生物学特性/表型/周期分类
基础医学引用本文复制引用
朱希山,施薇,台卫平,安广宇..脂肪与骨髓来源间充质干细胞生物学特性的比较[J].中国组织工程研究与临床康复,2011,15(32):5936-5940,5.
