摘要
Abstract
Objective To evaluate the methods of wound treatment after exposure to rabiest. Methods A Case-control study was conducted in 2005 and 2006 including 132 rabies patients (case) and 73 non- patients exposed to homologous rabies (control). Non- conditional logistic regression was used to analyze the effective methods of wound treatment and to evaluate its effect. Results 132 cases and controls were investigated. Compared to grade I exposure, 97.7% of cases and 91.8% of controls had grade Iiand IIIexposure (OR=3.73, 95%CI: 0.90 - 15.40). Compared to lower limb, 8.5% ofcases and 1.45% ofcontrols were exposed at head and face (OR=3.67, 95%CI: 1.96 ~6.87), 57.4% of cases and 31.0% of controls were at upper limb and trunk (OR= 12.00,95%CL 1.49-96.79) (Chi- square trend: Chi- square=20.88,P=0.000). 22.6% ofcases and 11.8% ofcontrols had more than 1 exposure location (OR=2.19, 95%CL 0.88-5.58), 84.8% ofcases and 71.2% ofcontrols had blood in wounds (OR=2.26, 95%CL 1.07-4.80). Treatment on wounds in medical institutions was a protection factor, with a OR of0.47(95% CI: 0.25-0.88) as compared with those untreated patients. 80.8% of cases and 97.4% of controls dealt with wounds at the same day with exposure (OR-0.11, 95%CI: 0.01-0.90). Meanwhile, disinfection or washing plus disinfection were effective measures, as compared with those untreated patients, their OR was 0.28 (95%CI 0.10-0.76) and 0.33(95%CI: 0.13-0.80), respectively. Conclusion Exposure degree, exposure location, number of exposure location, blood in wounds, wound treatment, method ofwound treatment and time of dealing with wounds are the significant factors associated with rabies invasion. The results suggest that wounds should be disinfected immediately in medical institutions after exposure to rabies.关键词
狂犬病/伤口处理/效果/病例对照研究Key words
Rabies/Deal with wounds/Effect/Case-control study
