重庆医学2011，Vol.40Issue(29)：2931-2932,2935,3.DOI:10.3969/j.issn.1671-8348.2011.29.007
早期妊娠流产患者应用米非司酮对两种激素受体损害的作用研究
The effect of different doses of mifepristone to the membrane estrogen receptor and progesterone receptor during early intrauterine pregnancy abortion
吴伟英 1谭广萍1
作者信息
- 1. 广西医科大学第四临床附属医院/广西壮族自治区柳州市工人医院,545005
- 折叠
摘要
Abstract
Objective To investiage the different doses of mifepristone to the membrane estrogen receptor and progesterone receptor during early intrauterine pregnancy abortion. Methods 72 cases of early pregnancy taken mifepristone leading to abortion were doseved. Patients according to administration were dosage divided into two groups with 200 mg/d of Group A and 150 mg/d of Group B. In adolition,27 cases of early pregranay who was processed with arlificial abortion was called Group C as control group. Completely spontaneous abortion rate, abortion time, and mifepristone influenced aderse reactions were observed in the three groups. The relationship between PR,ER expression in patients with early pregnancy uterine exuviate membrane and gestational period was checked. Results All group s postoperative recovery situation and complications were not statistically different. Then compared with B and C group,PR glands and stroma expression of Group A was statistially lower and the expression of ER glands and stroma was statistically higher. Conclusion High-dose of mifepristone have different degree of damage on membrane estrogen receptor and progesterone receptor during early intrauterine pregnancy abortion.关键词
米非司酮/妊娠/受体,雌激素/孕激素类Key words
mifepristone/ pregnancy/ receptors, estrogen/ progestins引用本文复制引用
吴伟英,谭广萍..早期妊娠流产患者应用米非司酮对两种激素受体损害的作用研究[J].重庆医学,2011,40(29):2931-2932,2935,3.
