摘要
Abstract
Objective To investigate the clinical pathologic feature and the diagnosis method about the solitary plasmacytoma of bone. Methods We collected and reviewed the clinical information of 6 cases of the final pathologic diagnosis solitary plasmacyoma of bone who were treated in our hospital from January, 1966 to December, 2009 , through the clinical feature, imageologic appearance, the detection of blood and urine, pathologic routine HE staining and immunohistochemical staining to analyze, and reviewed pertinent literature. Results All the 6 cases with the solitary plasmacytoma of bone were skeletal destruction of single region,especially frequent in the location of abundance splenic pulp,2 lesions involved the costal bone,2 leisons cranium,l leison thoracic vertebra and 1 leison involved shaft of femur,respectively,and more common in male than that in female(the ratio of male to female was 2 : 1). The clinical situations were the pain of single bone location, no anaemia, hypercalcinemia and the damage of renal function, negative urine Bence-Jones proteins. Immunohistochemical expressions were CD38 and(or)CD138 ,and monoclonal expreesions were light chain globulin κ(2 cases) and λ(4 cases). Conclusion The solitary plasmacytoma of bone rarely occurred,final diagosis is demanded to combine varietal information,and should excluse the multiple myeloma.关键词
浆细胞瘤/病理学,临床/诊断Key words
plasmacytoma/ pathology, clinical/ diagosis
