中山大学学报（自然科学版）2011，Vol.50Issue(4)：65-69,5.
混合溶剂热条件下DL-Trp晶体生成过程的研究
Investigation on Crystallization of DL-Tryptophan by Mixed Solvent-thermal Method
摘要
Abstract
The DL-tryptophan (DL-Trp) crystal was prepared by the mixed solvent-thermal method between neodymium carbonate and L-tryptophan. The structure was characterized by FTIR, single-crystal X-ray diffraction analyses. The results indicated that the cyrstallized DL-Trp molecule possessed a cen-trosymmetric monoclinic space group P2 (1) /c with a = 1. 89 08 (2) nm, b = 0. 572 67 (11) nm, c = 0. 930 32 (15) nm and Z =4. It showed a three-dimensional structure assembled by hydrogen bond of 'C-O----H-N' interactions. The reasons for changing in configuration and the mechanism of the reaction were investigated by the curves of optical rotation and reaction time. The result indicated the transformation in configuration was a gradual change process. The temperature around 90 t was important for configuration transforming of Tip.关键词
L-色氨酸/DL-色氨酸/混合溶剂热法/晶体/构型/转变Key words
L-tryptophan/ DL-tryptophan/ mixed solvent-thermal method/ crystal/ configuration transformation引用本文复制引用
王建,唐丽娟,刘玮炜,马卫兴,陈龙..混合溶剂热条件下DL-Trp晶体生成过程的研究[J].中山大学学报（自然科学版）,2011,50(4):65-69,5.基金项目
江苏省教育厅自然科学基金资助项目(08KJB1S0002) （08KJB1S0002）
江苏省“六大人才高峰”资助项目(07-A-024) （07-A-024）
江苏省海洋生物技术重点建设实验室开放基金资助项目(2010HS07) （2010HS07）
江苏省海洋资源开发研究院科技开放基金资助项目(JSIMR10E02) （JSIMR10E02）
淮海工学院博士科研启动基金资助项目(KQ09006) （KQ09006）
