李诺 1王江 1邓斌 1魏熙乐 1车艳秋 1贾晨辉 1郭义 2王超2
作者信息
- 1. 天津大学电气与自动化工程学院,天津300072
- 2. 天津中医药大学,天津300193
- 折叠
摘要
Abstract
Objective To observe the effect of acupuncture of Zusanli (ST 36) on electroencephalogram (EEG) so as to probe into its law in regulating the interconnectvity of brain functional network. Methods A total of 9 healthy young volunteer students (6 male, 3 female) participated in the present study. They were asked to take a dorsal position on a test-bed. EEG signals were acquired from 22 surface scalp electrodes (Fp1, Fp2, F7. F3, Fz, F4, F8, A1, T3, C3, C2, C4, T4, A2, T5. P3, P2, P4, T6, Oz, O1and O2) fixed on the subject's head. Acupuncture stimulation was applied to the right Zusanli (ST 36) by manipulating the filiform needle with uniform reducing-reinforcing method and at a frequency of about 50 cycles/min for 2 min. Then the stimulation was stopped for 10 min, and repeated once again (needle-twirling frequency ; 150 and 200 cycles/min). 3 times altogether. The acquired EEG data were analyzed by using coherence estimation method, average path length, average clustering coefficient, and the average degree of the articulation points (nodes) for analyzing the synchronization of EEG signals before, during and after acupuncture. Results In comparison with pre-acupuncture, the coherence amplitude values of EEG-6 (1 - 4 Hz) and y (31-47 Hz) waves were increased significantly after acupuncture of ST 36. No significant changes were found in the amplitude values of EEG-8 (5- 8 Hz), -α (9- 13 Hz) and-p" (14- 30 Hz) waves after acupuncture stimulation. During and after acupuncture, the synchronism values of EEG-6 waves of different leads and numbers of interconnectivity between every two brain functional regions in majority of the 9 volunteers were increased clearly. In all volunteers, the degree values of all nodes except A 1 and A2, the average clustering coefficients along with the increase of the threshold (r) , and the average path lengths of the brain functional network of EEG-5 waves during and after acupuncture were also increased evidently (the latter two items, P<0. 05), suggesting an increase of the information exchange and functional connectivity of different brain regions. Conclusion Acupuncture of Zusanli (ST 36) can increase the amplitude and synchronization of EEG-6 waves of different leads, and potentiate the functional interconnectivity of brain functional network.关键词
脑功能性网络/针刺/相干佑计/脑功能同步性/聚类系数/平均路径长度Key words
Brain functional network/ Acupuncture/ Coherence estimation/ Brain functional synchronization/ Clustering coefficient/Average path length分类
医药卫生
